Singapore’s Dental Research Paves the Way for Next-Gen Antiviral Oral Hygiene

Singapore’s Dental Research Paves the Way for Next-Gen Antiviral Oral Hygiene

In the global battle against viral infections, Singapore has emerged with a pioneering development in oral hygiene. A collaborative research endeavour between the National Dental Centre Singapore (NDCS) and the homegrown brand Pearlie White® has resulted in a state-of-the-art antiseptic mouth rinse. This product not only targets the reduction of viral loads in saliva but also heralds a new age for daily oral care routines.

At the core of this innovation was a study by the National Dental Research Institute Singapore (NDRIS) in 2020, which scrutinised the effectiveness of various mouth rinses on the salivary SARS-CoV-2 virus. The outcome of this study, centred on the efficacy of Cetylpyridinium Chloride (CPC), has been pivotal in formulating this new antiseptic rinse.

The impetus for the research, according to Associate Professor Jaya Seneviratne of NDRIS, was derived from his voluntary work during the pandemic. This sense of urgency led to the rapid development of the Pearlie White Defenze™ Antiseptic Fluoride Mouth Rinse, blending rigorous scientific research with Pearlie White®’s deep commercial expertise.

Professor Marco A Peres from NDCS, emphasised the wider impact of the mouth rinse, not only in public settings but also within medical environments where it could minimise cross-infection risks during aerosol-generating procedures. This mouth rinse is poised to provide a new layer of protection for healthcare providers.

Meticulously formulated, the Pearlie White Defenze™ mouth rinse marries synthetic antiviral agents with a selection of natural ingredients chosen for their proven benefits in oral health. The formulation eschews alcohol, parabens, and other harsh substances, reflecting the brand’s commitment to gentle yet efficacious oral care.

In line with Pearlie White’s dedication to inclusivity and safety, the product has undergone dermatological testing and is halal-certified, as well as gluten-free. Andy Ong, Pearlie White’s Managing Director, has expressed pride in this Singaporean innovation, underscoring its potential to revolutionise oral health standards on a global scale.

As the product awaits its official introduction to the market, further clinical trials will aim to substantiate its benefits and explore its role within dentistry and broader public health applications. This mouth rinse is expected to become an integral part of preventative health measures, offering a simple yet effective tool against viral transmissions.

The advancement in oral care demonstrated by this Singaporean-led research is a beacon of the nation’s commitment to addressing health challenges through innovation. As the dental community anticipates the integration of this rinse into daily practices, it represents not only progress in oral hygiene but also a testament to the proactive approach to health safety in the post-pandemic world.

This article is composed for informational purposes, reflecting the current research advancements by NDCS and Pearlie White® without the intention of endorsing specific products. It aims to provide an objective overview of the strides made in oral healthcare innovation.

For more information, please visit: